publications

publications by categories in reverse chronological order. generated by jekyll-scholar.

2025

  1. Method and system for spectral imaging of density, anisotropy, and orientation
    Shalin Mehta, Ivan Ivanov, and Li-Hao Yeh
    Jan 2025
    US Patent 12,209,951
  2. Method and system for quantitative three dimensional measurement of density, anisotropy, and orientation without label
    Shalin B. Mehta, Li-Hao Yeh, and Ivan Ivanov
    Jan 2025
    US Patent 12,306,102
  3. Global organelle profiling reveals subcellular localization and remodeling at proteome scale
    Marco Y Hein, Duo Peng, Verina Todorova, and 27 more authors
    Cell, 2025
  4. Ultrack: pushing the limits of cell tracking across biological scales
    Jordao Bragantini, Ilan Theodoro, Xiang Zhao, and 13 more authors
    Nature Methods, 2025
  5. Volumetric imaging of the 3D orientation of cellular structures with a polarized fluorescence light-sheet microscope
    Talon Chandler, Min Guo, Yijun Su, and 15 more authors
    Proceedings of the National Academy of Sciences, 2025
  6. Mapping virus infection dynamics across scales with computational imaging
    Talon Chandler, Deepika Sundarraman, Eduardo Hirata-Miyasaki, and 4 more authors
    In High-Throughput Biophotonics: Imaging, Spectroscopy, and Beyond X, 2025
  7. Mapping cell state dynamics with AI-enabled live cell imaging
    Shalin Mehta, Eduardo Hirata-Miyasaki, Talon Chandler, and 9 more authors
    In High-Throughput Biophotonics: Imaging, Spectroscopy, and Beyond X, 2025
  8. 3D computational imaging of dry mass and orientation
    Talon Chandler, Li-Hao Yeh, Ivan Ivanov, and 5 more authors
    In Quantitative Phase Imaging XI, 2025
  9. Enabling long-term studies of developing organs in zebrafish through quantitative phase imaging and virtual staining
    Eduardo Hirata-Miyasaki, Ziwen Liu, Tiger Lao, and 8 more authors
    In Quantitative Phase Imaging XI, 2025
  10. Robust virtual staining of landmark organelles with Cytoland
    Ziwen Liu, Eduardo Hirata-Miyasaki, Soorya Pradeep, and 17 more authors
    Nature Machine Intelligence, 2025
  11. Benchmarking and Evaluation of AI Models in Biology: Outcomes and Recommendations from the CZI Virtual Cells Workshop
    Elizabeth Fahsbender, Alma Andersson, Jeremy Ash, and 31 more authors
    arXiv preprint arXiv:2507.10502, 2025
  12. Observing biological spatio-angular structures and dynamics with statistical image reconstruction and polarized fluorescence microscopy
    Junyu Liu, Talon Chandler, Yue Li, and 18 more authors
    bioRxiv, 2025
  13. Embedding cell state dynamics via contrastive learning of representations of 3D dynamic imaging datasets
    Eduardo Hirata-Miyasaki, Soorya Pradeep, Ziwen Liu, and 10 more authors
    In NeurIPS 2025 Workshop for Imageomics: Discovering Biological Knowledge from Images Using AI, 2025
  14. Establishment and maintenance of robust organ-scale spatio-temporal organization
    Allyson Quinn Ryan, Tiger Lao, Akila Balasubramanian, and 9 more authors
    In SMT 2025, 2025

2024

  1. Mantis: high-throughput 4D imaging and analysis of the molecular and physical architecture of cells
    Ivan E Ivanov, Eduardo Hirata-Miyasaki, Talon Chandler, and 10 more authors
    PNAS nexus, 2024
  2. Mapping in toto immune cell dynamics during viral infection in zebrafish
    Deepika Sundarraman, Talon Chandler, Shalin Mehta, and 1 more author
    In APS March Meeting Abstracts, 2024
  3. Three-dimensional spatio-angular fluorescence microscopy with a polarized dual-view inverted selective-plane illumination microscope (pol-diSPIM)
    Talon Chandler, Min Guo, Yijun Su, and 15 more authors
    bioRxiv, 2024
  4. 4D computational imaging and deep learning
    Shalin B Mehta
    In Computational Optical Imaging and Artificial Intelligence in Biomedical Sciences, 2024
  5. Building momentum through networks: Bioimaging across the Americas
    Mariana De Niz, Rodrigo Escobedo Garcia, Celina Teran Ramirez, and 59 more authors
    Journal of microscopy, 2024
  6. Robust virtual staining of landmark organelles
    Ziwen Liu, Eduardo Hirata-Miyasaki, Soorya Pradeep, and 14 more authors
    bioRxiv, 2024
  7. Permittivity tensor imaging: modular label-free imaging of 3D dry mass and 3D orientation at high resolution
    Li-Hao Yeh, Ivan E Ivanov, Talon Chandler, and 12 more authors
    Nature Methods, 2024
  8. High Throughput Imaging and Analysis of Intracellular Dynamics with Correlative Label-Free and Fluorescence Microscopy.
    Ivan E Ivanov, Eduardo Hirata-Miyasaki, Talon Chandler, and 10 more authors
    Microscopy & Microanalysis, 2024
  9. waveOrder: generalist framework for label-agnostic computational microscopy
    Talon Chandler, Eduardo Hirata-Miyasaki, Ivan E Ivanov, and 6 more authors
    arXiv preprint arXiv:2412.09775, 2024
  10. SulstonNet: A computational pipeline to analyze high-throughput imaging of nematode embryogenesis.
    FM Celebi, S Chou, A Hamdoun, and 4 more authors
    In MOLECULAR BIOLOGY OF THE CELL, 2024
  11. Robust virtual staining of cellular landmarks in high-throughput correlative microscopy
    Ziwen Liu, Eduardo Hirata-Miyasaki, Soorya Pradeep, and 14 more authors
    In MOLECULAR BIOLOGY OF THE CELL, 2024
  12. Physics-informed computation of label-free and fluorescence microscopy data improves contrast, information content, and biophysical interpretation.
    T Chandler, I Ivanov, E Hirata-Miyasaki, and 4 more authors
    In MOLECULAR BIOLOGY OF THE CELL, 2024
  13. DynaCLR: Contrastive Learning of Cellular Dynamics with Temporal Regularization
    Eduardo Hirata-Miyasaki, Soorya Pradeep, Ziwen Liu, and 10 more authors
    arXiv e-prints, 2024

2023

  1. Systems and methods for three-dimensional fluorescence polarization via multiview imaging
    Hari Shroff, Abhishek Kumar, Shalin B Mehta, and 4 more authors
    Jun 2023
    US Patent 11,680,903
  2. Visualizing sphingosine-1-phosphate receptor 1 (S1P1) signaling during central nervous system de-and remyelination
    Ezzat Hashemi, Ezra Yoseph, Hsing-Chuan Tsai, and 6 more authors
    Cellular and Molecular Neurobiology, 2023
  3. MultiSero: an open-source multiplex-ELISA platform for measuring antibody responses to infection
    Janie R Byrum, Eric Waltari, Owen Janson, and 24 more authors
    Pathogens, 2023
  4. Development of POLArIS, a versatile probe for multi-color/multi-target orientation imaging in living cells
    Keisuke Sato, Nori Nakai-Kadowaki, Ayana Sugizaki, and 9 more authors
    In MOLECULAR BIOLOGY OF THE CELL, 2023
  5. AAV Immuno-Gene Therapy Delivers Vectorized Cytokines to Effectively Treat HighGrade Gliomas
    Nathalie Clement, Sarah Morris, Akela Kuwahara, and 8 more authors
    In MOLECULAR THERAPY, 2023
  6. Automated classification of time-course imaging data applied to nematode embryogenesis
    Prachee Avasthi, Feridun Mert Celebi, Keith Cheveralls, and 7 more authors
    2023

2022

  1. OpenCell: Endogenous tagging for the cartography of human cellular organization
    Nathan H Cho, Keith C Cheveralls, Andreas-David Brunner, and 24 more authors
    Science, 2022
  2. MultiSero: portable plate reader with on-board analysis for serosurveillance of Dengue infections with multiplex serology
    Lena Blackmon, Eric Waltari, Hongquan Li, and 8 more authors
    In Optics and Biophotonics in Low-Resource Settings VIII, 2022
  3. DynaMorph: self-supervised learning of morphodynamic states of live cells
    Zhenqin Wu, Bryant B Chhun, Galina Popova, and 6 more authors
    Molecular Biology of the Cell, 2022
  4. Correlative imaging of the spatio-angular dynamics of biological systems with multimodal instant polarization microscope
    Ivan E Ivanov, Li-Hao Yeh, Juan A Perez-Bermejo, and 4 more authors
    Biomedical Optics Express, 2022
  5. Statistical topology of the streamlines of a two-dimensional flow
    Mason Kamb, Janie Byrum, Greg Huber, and 4 more authors
    Journal of Physics A: Mathematical and Theoretical, 2022

2021

  1. POLArIS, a versatile probe for molecular orientation, revealed actin filaments associated with microtubule asters in early embryos
    Ayana Sugizaki, Keisuke Sato, Kazuyoshi Chiba, and 9 more authors
    Proceedings of the National Academy of Sciences, 2021
  2. Pycro-Manager: open-source software for customized and reproducible microscope control
    Henry Pinkard, Nico Stuurman, Ivan E Ivanov, and 20 more authors
    Nature methods, 2021
  3. Contractility, focal adhesion orientation, and stress fiber orientation drive cancer cell polarity and migration along wavy ECM substrates
    Robert S Fischer, Xiaoyu Sun, Michelle A Baird, and 8 more authors
    Proceedings of the National Academy of Sciences, 2021
  4. Human microglia states are conserved across experimental models and regulate neural stem cell responses in chimeric organoids
    Galina Popova, Sarah S Soliman, Chang N Kim, and 16 more authors
    Cell stem cell, 2021

2020

  1. Scalable analysis of architecture of brain tissue with label-free imaging and deep learning (Conference Presentation)
    Syuan-Ming Guo, Matt Keefe, David Shin, and 4 more authors
    In Label-free Biomedical Imaging and Sensing (LBIS) 2020, 2020
  2. Revealing architectural order with quantitative label-free imaging and deep learning
    Syuan-Ming Guo, Li-Hao Yeh, Jenny Folkesson, and 11 more authors
    elife, 2020
  3. uPTI: uniaxial permittivity tensor imaging of intrinsic density and anisotropy
    Li-Hao Yeh, Ivan E Ivanov, Syuan-Ming Guo, and 11 more authors
    bioRxiv, 2020
  4. uPTI: uniaxial permittivity tensor imaging of intrinsic density and anisotropy (preprint)
    Li-Hao Yeh, Ivan E Ivanov, Syuan-Ming Guo, and 11 more authors
    2020

2019

  1. Learning Biological Structures from Birefringence images with Deep Neural Networks
    Syuan-Ming Guo, Anitha Krishnan, Jenny Folkesson, and 2 more authors
    In Mathematics in Imaging, 2019

2018

  1. Partially coherent microscope in phase space
    Shalin B Mehta and Colin JR Sheppard
    Journal of the Optical Society of America A, 2018
  2. Partially coherent imaging in phase space
    Colin JR Sheppard and Shalin B Mehta
    In Unconventional Optical Imaging, 2018
  3. Three-dimensional fluorophore orientation imaging with multiview polarized microscopy
    Talon Chandler, Min Guo, Shalin Mehta, and 4 more authors
    In Mathematics in Imaging, 2018

2017

  1. Actin retrograde flow actively aligns and orients ligand-engaged integrins in focal adhesions
    Vinay Swaminathan, Joseph Mathew Kalappurakkal, Shalin B Mehta, and 9 more authors
    Proceedings of the National Academy of Sciences, 2017
  2. Direction of actin flow dictates integrin LFA-1 orientation during leukocyte migration
    Pontus Nordenfelt, Travis I Moore, Shalin B Mehta, and 11 more authors
    Nature communications, 2017
  3. Phase transition and liquid crystalline organization of colloidal graphene oxide as a function of pH
    Rachel Tkacz, Md Joynul Abedin, Phillip Sheath, and 4 more authors
    Particle & Particle Systems Characterization, 2017
  4. Analysis of septin reorganization at cytokinesis using polarized fluorescence microscopy
    Molly McQuilken, Maximilian S Jentzsch, Amitabh Verma, and 3 more authors
    Frontiers in cell and developmental biology, 2017
  5. Cytokinesis in vertebrate cells initiates by contraction of an equatorial actomyosin network composed of randomly oriented filaments
    Felix Spira, Sara Cuylen-Haering, Shalin Mehta, and 6 more authors
    Elife, 2017
  6. Single-fluorophore orientation determination with multiview polarized illumination: modeling and microscope design
    Talon Chandler, Shalin Mehta, Hari Shroff, and 2 more authors
    Optics Express, 2017

2016

  1. Dissection of molecular assembly dynamics by tracking orientation and position of single molecules in live cells
    Shalin B Mehta, Molly McQuilken, Patrick J La Riviere, and 5 more authors
    Proceedings of the National Academy of Sciences, 2016
  2. Phase microscope imaging in phase space
    Colin JR Sheppard and Shalin B Mehta
    In Quantitative Phase Imaging II, 2016
  3. Revealing Molecular Order in Live Cells
    Shalin B Mehta, Rudolf Oldenbourg, and Tomomi Tani
    Optics and Photonics News, 2016
  4. Imaging molecular order of dynamic cytoskeletal assemblies in live cells with single molecule sensitivity.
    SB Mehta, M McQuilken, H Ishii, and 5 more authors
    In MOLECULAR BIOLOGY OF THE CELL, 2016

2015

  1. Polarized light microscopy in reproductive and developmental biology
    Maki Koike-Tani, Tomomi Tani, Shalin B Mehta, and 2 more authors
    Molecular reproduction and development, 2015
  2. MultiFocus Polarization Microscope (MF-PolScope) for 3D polarization imaging of up to 25 focal planes simultaneously
    Sara Abrahamsson, Molly McQuilken, Shalin B Mehta, and 7 more authors
    Optics express, 2015
  3. Polarized fluorescence microscopy to study cytoskeleton assembly and organization in live cells
    Molly McQuilken, Shalin B Mehta, Amitabh Verma, and 3 more authors
    Current protocols in cell biology, 2015
  4. Equivalent of the point spread function for partially coherent imaging
    Shalin B Mehta and Colin JR Sheppard
    Optica, 2015
  5. Adaptation of Actin Cytoskeleton during Suspended Animation
    Clara Kao, Mark A Messerli, Jonathan D Gitlin, and 1 more author
    Biophysical Journal, 2015
  6. Leukocyte integrin LFA-1 is aligned and oriented by actin flow during cell migration.
    Vinay Swaminathan, Joseph Mathew Kalappurakkal, Shalin B Mehta, and 9 more authors
    In MOLECULAR BIOLOGY OF THE CELL, 2015
  7. Three dimensional imaging of molecular order of the cytoskeleton by confocal fluorescence polarization microscopy
    SB Mehta, RS Fischer, FG Spira, and 3 more authors
    In MOLECULAR BIOLOGY OF THE CELL, 2015
  8. Position and orientation mapping of dynamic biomolecular assemblies in living cells with single molecule sensitivity
    SB Mehta, M McQuilken, P Occhipinti, and 5 more authors
    In MOLECULAR BIOLOGY OF THE CELL, 2015
  9. Dynamics of Polymeric Protein Assemblies in Live Cells Revealed by Fluorescence Polarization Imaging of Single Molecules
    Shalin B Mehta, Molly McQuilken, Patricia Occhipinti, and 4 more authors
    Biophysical Journal, 2015
  10. Actin retrograde flow orients and aligns activated, ligand-engaged integrins in focal adhesions.
    V Swaminathan, JK Mathew, P Nordenfelt, and 7 more authors
    In MOLECULAR BIOLOGY OF THE CELL, 2015

2014

  1. Septin assemblies form by diffusion-driven annealing on membranes
    Andrew A Bridges, Huaiying Zhang, Shalin B Mehta, and 3 more authors
    Proceedings of the National Academy of Sciences, 2014
  2. pH dependent isotropic to nematic phase transitions in graphene oxide dispersions reveal droplet liquid crystalline phases
    Rachel Tkacz, Rudolf Oldenbourg, Shalin B Mehta, and 3 more authors
    Chemical communications, 2014
  3. Image simulation for biological microscopy: microlith
    Shalin B Mehta and Rudolf Oldenbourg
    Biomedical optics express, 2014
  4. Molecular order in graphene-oxide suspensions and graphene-based films: What do we learn from it?
    Rachel Tkacz, Rudolf Oldenbourg, Shalin Mehta, and 1 more author
    In AIChE Annual Meeting 2014, 2014
  5. Shs1 is required for an organized septin higher order structure in vivo.
    M McQuilken, S Abrahamsson, S Mehta, and 4 more authors
    In MOLECULAR BIOLOGY OF THE CELL, 2014

2013

  1. Polarized light imaging of birefringence and diattenuation at high resolution and high sensitivity
    Shalin B Mehta, Michael Shribak, and Rudolf Oldenbourg
    Journal of optics, 2013
  2. Superresolution by image scanning microscopy using pixel reassignment
    Colin JR Sheppard, Shalin B Mehta, and Rainer Heintzmann
    Optics letters, 2013
  3. Phase contrast microscopy-Methods and modeling
    Colin JR Sheppard, Shan Shan Kou, and Shalin Mehta
    In Novel Techniques in Microscopy, 2013
  4. Fluorescent Single Molecule Orientation Imaging for Exploring 3D Architectural Dynamics of Cytoskeletal Protein Assembly in Living Cells
    Tomomi Tani, Shalin Mehta, Bradley S DeMay, and 3 more authors
    Biophysical Journal, 2013
  5. 2P298 Fluorescent Single Molecule Orinetation Imaging in Living Cells (27. Bioimaging, Poster)
    Tomomi Tani, Shalin Mehta, Rudolf Oldenbourg, and 1 more author
    Seibutsu Butsuri, 2013
  6. Application of Polarized Fluorescence Microscopy to the Assembly and Dynamics of Septins
    M McQuilken, S Abrahamsson, S Mehta, and 4 more authors
    In MOLECULAR BIOLOGY OF THE CELL, 2013

2012

  1. Three-level filter for increased depth of focus and Bessel beam generation
    Colin JR Sheppard and Shalin Mehta
    Optics express, 2012
  2. Phase space analysis of partially coherent imaging in a microscope
    Colin Sheppard and Shalin S Mehta
    In Frontiers in Optics, 2012
  3. Single molecule analysis of septin assembly
    A Bridges, S Mehta, T Tani, and 1 more author
    In MOLECULAR BIOLOGY OF THE CELL, 2012

2011

  1. FAT10 mediates the effect of TNF-αin inducing chromosomal instability
    Jianwei Ren, Yu Wang, Yun Gao, and 2 more authors
    Journal of cell science, 2011
  2. 2M1548 Dark-field imaging of beating axoneme: Correlation between bend propagation and structural changes in the axoneme (Molecular motor 3, The 48th Annual Meeting of the Biophysical Society of Japan)
    Naoki Noda, Shalin Mehta, Colin Sheppard, and 1 more author
    Seibutsu Butsuri, 2011
  3. 2M1548 暗視野顕微鏡による軸糸屈曲運動イメージング: 屈曲伝播と軸糸内部構造の相関を探る (分子モーター 3, 第 49 回日本生物物理学会年会)
    Noda Naoki, Mehta Shalin, Sheppard Colin, and 1 more author
    生物物理, 2011

2010

  1. Phase-space representation of partially coherent imaging systems using the Cohen class distribution
    Shalin B Mehta and Colin JR Sheppard
    Optics letters, 2010
  2. Using the phase-space imager to analyze partially coherent imaging systems: bright-field, phase contrast, differential interference contrast, differential phase contrast, and spiral phase contrast
    Shalin B Mehta and Colin JR Sheppard
    Journal of Modern Optics, 2010
  3. Sample-less calibration of the differential interference contrast microscope
    Shalin B Mehta and Colin JR Sheppard
    Applied optics, 2010
  4. Image Formation and Analysis of Coherent Microscopy and Beyond–Toward Better Imaging and Phase Recovery
    Shan Shan Kou, Shalin B Mehta, Shakil Rehman, and 1 more author
    In Coherent Light Microscopy: Imaging and Quantitative Phase Analysis, 2010
  5. Phase-Space Perspective of Partially Coherent Imaging: Applications to Biological Phase Microscopy
    Shalin B. Mehta
    National University of Singapore, 2010
  6. Partially coherent image formation in Asymmetric Illumination-based Differential Phase Contrast (AIDPC) and phase-retrieval
    Shalin B Mehta and Colin JR Sheppard
    In AIP Conference Proceedings, 2010

2009

  1. Quantitative phase-gradient imaging at high resolution with asymmetric illumination-based differential phase contrast
    Shalin B Mehta and Colin JR Sheppard
    Optics letters, 2009
  2. Linear Phase-gradient Imaging with Asymmetric Illumination based Differential Phase Contrast (AIDPC)
    Shalin B Mehta and Colin J Sheppard
    In Novel Techniques in Microscopy, 2009
  3. Transfer function analysis of partially coherent phase imaging methods and evaluation for quantitative imaging
    Shalin B Mehta and Colin J Sheppard
    In Frontiers in Optics, 2009
  4. Full-field phase-gradient contrast methods for label-free quantitative imaging of cellular morphology: AIDPC and DIC
    Shalin B Mehta and CJR Sheppard
    Focus on Microscopy, Krakow, Poland) URL: http://www. focusonmicroscopy. org/2009/PDF/396 Mehta. pdf, 2009
  5. Quantitative Phase Imaging in Microscopy
    Colin JR Sheppard, Shan S Kou, and Shalin Mehta
    In Fringe 2009: 6th International Workshop on Advanced Optical Metrology, 2009
  6. A New Phase-Correlation Based Gradient Registration Approach for Phase-retrieval with DIC and DPC
    Shalin B Mehta and Colin JR Sheppard
    In Signal Recovery and Synthesis, 2009

2008

  1. Partially coherent image formation in differential interference contrast (DIC) microscope
    Shalin B Mehta and Colin J Sheppard
    Optics Express, 2008
  2. Asymmetric illumination based differential phase contrast (AI-DPC) for full-field transmission imaging of phase information in biological specimens
    Shalin B Mehta and CJR Sheppard
    In Focus on Microscopy Conference Series, Osaka-Awaji, Japan, April, 2008

2004

  1. On wavelets and fractal modulation
    Shalin Mehta
    Dhirubhai Ambani Institute of Information and Communication Technology, 2004